WebJul 16, 2024 · phosphonate phosphonic acid phosphonic monoester Introduction Phosphinic and phosphonic derivatives, especially the corresponding phosphinates and phosphonates may be important intermediates in organophosphorus chemistry. In organic chemistry, phosphonates or phosphonic acids are organophosphorus compounds containing C−PO(OR)2 groups (where R = alkyl, aryl, or just hydrogen). Phosphonic acids, typically handled as salts, are generally nonvolatile solids that are poorly soluble in organic solvents, but soluble in water and … See more Phosphonates feature tetrahedral phosphorus centers. They are structurally closely related to (and often prepared from) phosphorous acid. Phosphonate salts are the result of deprotonation of … See more Bisphosphonates Compounds containing 2 geminal phosphonate groups are known as bisphosphonates. They were first synthesized in 1897 by Von Baeyer and Hofmann and now form the basis for an important class of … See more In 1998 the consumption of phosphonates was 56,000 tons worldwide – 40,000 tons in the US, 15,000 tons in Europe and less than 800 tons in Japan. The demand of phosphonates grows steadily at 3% annually. Metal chelants See more Several methods exist for the preparation of phosphonic acids and their salts. From phosphonic acid Most processes … See more Hydrolysis Phosphonate esters are generally susceptible to hydrolysis under both acidic and basic conditions. Cleavage of the P-C bond is harder but can be achieved under aggressive conditions. O=PC(OR)2 + 2 H2O … See more Phosphonates are one of the three sources of phosphate intake in biological cells. The other two are inorganic phosphate and organophosphates. The naturally occurring phosphonate 2-aminoethylphosphonic acid was first identified in 1959 in … See more In medicine, phosphonates and bisphosphonates are commonly used as inhibitors of enzymes which utilize phosphates and … See more
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WebTenofovir disoproxil is a pro-drug form of tenofovir phosphonate, which is liberated intracellularly and converted to tenofovir disphophate. [29] It is marketed by Gilead Sciences (as the fumarate, abbreviated TDF). [30] Tenofovir disoproxil is also available in pills which combine a number of antiviral drugs into a single dose. WebMethylphosphonate(2-) is an organophosphonate oxoanion obtained by deprotonation of the phosphonate OH groups of methylphosphonic acid. It is a conjugate base of a methylphosphonate(1-). ChEBI. Methylphosphonate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). lead painted windows
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WebDiethyl (hydroxymethyl)phosphonate C5H13O4P CID 76513 - structure, chemical names, physical and chemical properties, classification, patents, literature ... WebOn this Wikipedia the language links are at the top of the page across from the article title. Go to top. WebSodium xylene sulfonate C8H11NaO3S CID 71775948 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... lead paint form nj